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Research

We study the psychological, neural and molecular processes that contribute to drug and alcohol abuse. Central to this work is the hypothesis that drug addiction is a behavioural disorder that is strongly influenced by associative and non-associative learning. This research is funded by the Canadian Institutes of Health Research and Fonds de recherche du Québec - Santé.

A second line of research, funded by the Natural Sciences and Engineering Research Council, examines the neural regulation of extinction learning in animal models of appetitive instrumental and Pavlovian conditioning.

Our research uses animal models combined with neuropharmacology, optogenetics, chemogenetics, in vitro electrophysiology and immunohistochemistry.

Here are our publications.

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Orange neurons are VTA cells co-expressing cre recombinase and hM4D1-mCherry (Image by Milan Valyear)

Orange neurons are VTA cells co-expressing cre recombinase and hM4D1-mCherry (Image by Milan Valyear)

Infrastructure

Core infrastructure includes operant conditioning chambers (n=42), in vivo optogenetics, slice electrophysiology rig, transgenic TH::Cre rat colony, molecular biology core facility, Center for Microscopy and Cellular Imaging (CMCI) and more.

Med Associates operant conditioning chambers

Med Associates operant conditioning chambers

Fluorescence- and optogenetics-enhanced slice electrophysiology rig

Fluorescence- and optogenetics-enhanced slice electrophysiology rig

 

Funding

Current and past research made possible by generous support from: